5-Aminosalicylic acid for the treatment of inflammatory bowel disease
نویسندگان
چکیده
منابع مشابه
Role of 5-aminosalicylic acid (5-ASA) in treatment of inflammatory bowel disease: a systematic review.
Authors' objectives To perform a systematic review of the efficacy of 5-aminosalicylic acid (5-ASA) compounds (oral and topical) in the treatment of inflammatory bowel disease (IBD), both ulcerative colitis (UC) and Crohn's disease (CD), in the acute phase for inducing remission and for the prevention of relapses or recurrences. Also, to evaluate the influence of several factors (such as dosage...
متن کاملSynthesis and evaluation of a prodrug of 5-aminosalicylic acid for the treatment of ulcerative colitis
Objective(s): This study is aimed to design and synthesize a prodrug of 5-aminosalicylic acid and evaluate its ameliorative effect on experimental ulcerative colitis (UC).Materials and Methods: 5-Aminosalicylic acid-alanine (5-ASA-ALA) was synthesized and characterized. Its stability study was conducted in rat plasma and in the gastroint...
متن کاملThe value of 5-aminosalicylic acid in inflammatory bowel disease for patients intolerant or allergic to sulphasalazine.
The use of sulphasalazine in inflammatory bowel disease is often limited by intolerance or allergy. In previous studies 5-aminosalicylic acid (5ASA), the active ingredient of sulphasalazine, coated with an acrylic resin, has been shown to be as effective as sulphasalazine in maintaining remission. In this study coated 5ASA was given to 37 patients intolerant or allergic to sulphasalazine. Thirt...
متن کامل5-ASAs in the Treatment of Inflammatory Bowel Disease
Epidemiologic data on IBD are fractionated into the pigeon holes of separate diagnoses, with an incidence of 7 to 9 per 100,000 and a prevalence of 200 to 250 per 100,000 for UC; the incidence and prevalence of CD is 6 to 8 per 100,000 and 130 to 200 per 100,000, respectively. Although there are patients who fall more clearly into one category than another, the concept of indeterminate colitis ...
متن کاملINFLAMMATION AND INFLAMMATORY BOWEL DISEASE Birth outcome in women exposed to 5-aminosalicylic acid during pregnancy: a Danish cohort study
Background: 5-Aminosalicylic acid (5-ASA) preparations are the firstline drugs in the treatment of inflammatory bowel disease. Data on the safety of these drugs in pregnancy are sparse. Aims: To examine the risk of adverse birth outcome in women who were prescribed 5-ASA drugs during pregnancy. Patients: Women were included in the study if they were prescribed 5-ASA drugs immediately before or ...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1984
ISSN: 0016-5085
DOI: 10.1016/0016-5085(84)90750-9